--- title: "Proton Pump Inhibitors: How Long Term Use is Linked to Deadly Side Effects" description: Proton Pump Inhibitors, or PPIs, reduce stomach acid by blocking the enzyme that produces the acid. Learn more about potential side effects image: https://news.bartdurham.com/hubfs/photos/Pills-Drugs-1.png --- [![BART DURHAM INJURY LAW](https://news.bartdurham.com/hubfs/raw_assets/public/Bart_Durham_December2023/images/BD-VECTOR_MAIN-NAV-LOGO-WHITE.svg "BART DURHAM INJURY LAW")](https://bartdurham.com/) - Our Law Firm - [About Us](https://bartdurham.com/about-us/) - [Remembering Bart](https://bartdurham.com/about-us/meet-bart/) - [Our Team](https://bartdurham.com/our-team) - [Community Service](https://bartdurham.com/category/community-celebrations) - [Attorneys](https://bartdurham.com/attorneys/) - [Blair Durham](https://bartdurham.com/attorneys/blair-durham/) - [Chaucey Fuller](https://bartdurham.com/attorneys/chaucey-fuller/) - [Rich Cassidy](https://bartdurham.com/attorneys/rich-cassidy/) - [Annie Berry](https://bartdurham.com/attorneys/annie-berry-2/) - News - [News](https://news.bartdurham.com/blog) - [Resource Center](https://bartdurham.com/personal-injury-law-resource-center/) - [FAQ](https://bartdurham.com/faq/) - [Videos](https://bartdurham.com/videos/) - [The Law, Your Insurance & Your Rights](https://bartdurham.com/personal-injury-lawyer/the-law-your-insurance-your-rights/) - [Our Case Results](https://bartdurham.com/results/) - Areas of Practice - [Automobile Accidents](https://bartdurham.com/automobile-accidents/) - [Car Accidents](https://bartdurham.com/automobile-accidents/car-accidents/) - [Truck Accidents](https://bartdurham.com/automobile-accidents/truck-accidents/) - [Public Transportation and Commercial Vehicle Accidents](https://bartdurham.com/automobile-accidents/public-transportation-and-commercial-vehicle-accidents/) - [Motorcycle Accidents](https://bartdurham.com/automobile-accidents/motorcycle-accidents/) - More - [Pedestrian Accidents](https://bartdurham.com/automobile-accidents/pedestrian-accidents/) - [DUI Accidents](https://bartdurham.com/automobile-accidents/dui-accidents-injuries/) - [Rear End Collisions](https://bartdurham.com/automobile-accidents/rear-end-collisions/) - [Rollover Accidents](https://bartdurham.com/automobile-accidents/car-accidents/one-car-accidents/vehicle-rollover/) - [Personal Injury Lawyer](https://bartdurham.com/personal-injury-lawyer/) - [Catastrophic Injuries](https://bartdurham.com/personal-injury-lawyer/catastrophic-injuries/) - [Workplace Accidents](https://bartdurham.com/personal-injury-lawyer/workplace-injury-lawyers/) - [Product Liability](https://bartdurham.com/personal-injury-lawyer/product-liability-lawyer/) - [Medical Malpractice](https://bartdurham.com/personal-injury-lawyer/medical-malpractice-lawyer/) - [Recalls](https://bartdurham.com/recalls/) - [Farm Equipment Injury](https://bartdurham.com/personal-injury-lawyer/kentucky-farm-equipment-injury/) - [Contact Us](https://bartdurham.com/contact/) 800.844.1712 - Our Law Firm - [About Us](https://bartdurham.com/about-us/) - [Remembering Bart](https://bartdurham.com/about-us/meet-bart/) - [Our Team](https://bartdurham.com/our-team) - [Community Service](https://bartdurham.com/category/community-celebrations) - [Attorneys](https://bartdurham.com/attorneys/) - [Blair Durham](https://bartdurham.com/attorneys/blair-durham/) - [Chaucey Fuller](https://bartdurham.com/attorneys/chaucey-fuller/) - [Rich Cassidy](https://bartdurham.com/attorneys/rich-cassidy/) - [Annie Berry](https://bartdurham.com/attorneys/annie-berry-2/) - News - [News](https://news.bartdurham.com/blog) - [Resource Center](https://bartdurham.com/personal-injury-law-resource-center/) - [FAQ](https://bartdurham.com/faq/) - [Videos](https://bartdurham.com/videos/) - [The Law, Your Insurance & Your Rights](https://bartdurham.com/personal-injury-lawyer/the-law-your-insurance-your-rights/) - [Our Case Results](https://bartdurham.com/results/) - Areas of Practice - [Automobile Accidents](https://bartdurham.com/automobile-accidents/) - [Car Accidents](https://bartdurham.com/automobile-accidents/car-accidents/) - [Truck Accidents](https://bartdurham.com/automobile-accidents/truck-accidents/) - [Public Transportation and Commercial Vehicle Accidents](https://bartdurham.com/automobile-accidents/public-transportation-and-commercial-vehicle-accidents/) - [Motorcycle Accidents](https://bartdurham.com/automobile-accidents/motorcycle-accidents/) - More - [Pedestrian Accidents](https://bartdurham.com/automobile-accidents/pedestrian-accidents/) - [DUI Accidents](https://bartdurham.com/automobile-accidents/dui-accidents-injuries/) - [Rear End Collisions](https://bartdurham.com/automobile-accidents/rear-end-collisions/) - [Rollover Accidents](https://bartdurham.com/automobile-accidents/car-accidents/one-car-accidents/vehicle-rollover/) - [Personal Injury Lawyer](https://bartdurham.com/personal-injury-lawyer/) - [Catastrophic Injuries](https://bartdurham.com/personal-injury-lawyer/catastrophic-injuries/) - [Workplace Accidents](https://bartdurham.com/personal-injury-lawyer/workplace-injury-lawyers/) - [Product Liability](https://bartdurham.com/personal-injury-lawyer/product-liability-lawyer/) - [Medical Malpractice](https://bartdurham.com/personal-injury-lawyer/medical-malpractice-lawyer/) - [Recalls](https://bartdurham.com/recalls/) - [Farm Equipment Injury](https://bartdurham.com/personal-injury-lawyer/kentucky-farm-equipment-injury/) - [Contact Us](https://bartdurham.com/contact/) [![BART DURHAM INJURY LAW](https://news.bartdurham.com/hubfs/raw_assets/public/Bart_Durham_December2023/images/BD-VECTOR_MAIN-NAV-LOGO-WHITE.svg "BART DURHAM INJURY LAW")](https://bartdurham.com/) ![Proton Pump Inhibitors: How Long Term Use is Linked to Deadly Side Effects](https://news.bartdurham.com/hubfs/photos/Pills-Drugs-1.png) # Proton Pump Inhibitors: How Long Term Use is Linked to Deadly Side Effects [Bart Durham Injury Law](https://news.bartdurham.com/blog/author/bart-durham-injury-law) [Defective Medical Devices](https://news.bartdurham.com/blog/tag/defective-medical-devices), [Dangerous or Defective Drugs](https://news.bartdurham.com/blog/tag/dangerous-or-defective-drugs) ## Proton Pump Inhibitors: How Long Term Use is Linked to Deadly Side Effects *Proton Pump Inhibitors, or PPIs, reduce stomach acid by blocking the enzyme that produces the acids.* PPIs are used to help prevent heartburn, stomach ulcers, and other issue caused by excess stomach acid. Some PPIs are prescription only but some are available over the counter. [A 2016 study has shown](https://www.ncbi.nlm.nih.gov/pubmed/27080976) that long-term use of PPIs has been linked to chronic kidney disease, as well as other side effects, some of which could be deadly. ### Potential PPI Side Effects![ppi side effects medical malfunction bart durham - Bart Durham](https://news.bartdurham.com/hs-fs/hubfs/Imported_Blog_Media/ppi-side-effects-medical-malfunction-bart-durham.jpg?width=350&height=233&name=ppi-side-effects-medical-malfunction-bart-durham.jpg) PPIs have a long list of side effects ranging from [mild discomforts like headaches or nausea](https://www.medicinenet.com/proton-pump_inhibitors/article.htm) to severe, [life-threatening side effects like nephritis and kidney failure](https://www.webmd.com/heartburn-gerd/news/20160608/proton-pump-inhibitor-health-risks#1). Long-term use has even been linked to a higher risk of heart attacks and certain types of cancers. But the most common, life-threatening side effect of long-term PPI use is chronic kidney disease or CKD. In fact, [long-term PPI users are 28% more likely to suffer from CKD and 95% more likely to experience kidney failure ](https://www.ncbi.nlm.nih.gov/pubmed/27080976)when compared to those who used histamine H2 receptor blockers to manage their acid-related issue instead. CKD happens silently and gradually which means you may not notice it right away. CKD can progress far enough to requiring dialysis or even a kidney transplant. If CKD is not treated, it could lead to total kidney failure. ### Legal Action Has Been Taken Against PPI Manufacturers There are currently thousands of lawsuits against the makers of these PPIs. These lawsuits claim manufacturing companies did not properly warn users or medical professionals about the potential life-threatening kidney risks associated with long-term PPI use. Because of this, physicians did not know to warn patients of the potential side effects and users did not know the risks when getting the medications over the counter. ### What Should You Do if You Used PPIs Longterm? If you or a loved one have been taking PPIs long term, call your doctor about alternatives to PPIs and potential health risk. If you believe your health has been affected by the long-term use of these drugs or had a loved one experience kidney failure while on these drugs, give us a call to schedule a free initial consultation. --- #### Tag: [Defective Medical Devices](https://news.bartdurham.com/blog/tag/defective-medical-devices) [Dangerous or Defective Drugs](https://news.bartdurham.com/blog/tag/dangerous-or-defective-drugs) #### Share: - [Follow us on Facebook](http://www.facebook.com/share.php?u=https://news.bartdurham.com/blog/2018/09/proton-pump-inhibitors-how-long-term-use-is-linked-to-deadly-side-effects) - - [Follow us on Linkedin](http://www.linkedin.com/shareArticle?mini=true&url=https://news.bartdurham.com/blog/2018/09/proton-pump-inhibitors-how-long-term-use-is-linked-to-deadly-side-effects) - [Follow us on Pinterest](http://pinterest.com/pin/create/button/?url=https://news.bartdurham.com/blog/2018/09/proton-pump-inhibitors-how-long-term-use-is-linked-to-deadly-side-effects&text=Proton%20Pump%20Inhibitors:%20How%20Long%20Term%20Use%20is%20Linked%20to%20Deadly%20Side%20Effectsdescription=Proton%20Pump%20Inhibitors,%20or%20PPIs,%20reduce%20stomach%20acid%20by%20blocking%20the%20enzyme%20that%20produces%20the%20acids.&media=https://cdn2.hubspot.net/hubfs/4679191/photos/Pills-Drugs-1.png) --- #### [Night Driving Safety Tips Previous Post](https://news.bartdurham.com/blog/2018/09/night-driving-safety-tips) #### [Common Auto Defects & Warning Signs Next Post](https://news.bartdurham.com/blog/2018/09/common-auto-defects-warning-signs) This is a search field with an auto-suggest feature attached. - There are no suggestions because the search field is empty. ### Category - [Car Accidents (479)](https://news.bartdurham.com/blog/tag/car-accidents) - [Accident (291)](https://news.bartdurham.com/blog/tag/accident) - [Dangerous or Defective Drugs (259)](https://news.bartdurham.com/blog/tag/dangerous-or-defective-drugs) - [Big Truck Accidents (185)](https://news.bartdurham.com/blog/tag/big-truck-accidents) - [Design & Manufacturing Defects (184)](https://news.bartdurham.com/blog/tag/design-manufacturing-defects) ### Popular Posts [Bart Durham Injury Law](https://news.bartdurham.com/blog/author/bart-durham-injury-law) 01/29/2024 [Dangerous or Defective Drugs](https://news.bartdurham.com/blog/tag/dangerous-or-defective-drugs), [Injuries](https://news.bartdurham.com/blog/tag/injuries), [Mass Tort](https://news.bartdurham.com/blog/tag/mass-tort), [Personal Injury Lawyer](https://news.bartdurham.com/blog/tag/personal-injury-lawyer) [Ozempic, Wegovy, Rybelsus, Saxenda, Mounjaro, and Trulicity Linked to Gastroparesis and Stomach Paralysis](https://news.bartdurham.com/blog/ozempic-wegovy-rybelsus-saxenda-mounjaro-and-trulicity-linked-to-gastroparesis-and-stomach-paralysis) [Bart Durham Injury Law](https://news.bartdurham.com/blog/author/bart-durham-injury-law) 01/28/2025 [Car Accidents](https://news.bartdurham.com/blog/tag/car-accidents), [Kentucky](https://news.bartdurham.com/blog/tag/kentucky), [Tennessee](https://news.bartdurham.com/blog/tag/tennessee), [Big Truck Accidents](https://news.bartdurham.com/blog/tag/big-truck-accidents), [Accident](https://news.bartdurham.com/blog/tag/accident), [Personal Injury Lawyer](https://news.bartdurham.com/blog/tag/personal-injury-lawyer), [Commercial Vehicle Accidents](https://news.bartdurham.com/blog/tag/commercial-vehicle-accidents) [Do These 5 Things After a Big Truck Wreck](https://news.bartdurham.com/blog/2017/06/do-these-5-things-after-a-big-truck-wreck) [Bart Durham Injury Law](https://news.bartdurham.com/blog/author/bart-durham-injury-law) 01/31/2025 [Car Accidents](https://news.bartdurham.com/blog/tag/car-accidents), [Drunk Driving Accidents](https://news.bartdurham.com/blog/tag/drunk-driving-accidents), [Fatal Accidents](https://news.bartdurham.com/blog/tag/fatal-accidents), [Accident](https://news.bartdurham.com/blog/tag/accident) [Common Car Accidents (And Who's at Fault)](https://news.bartdurham.com/blog/common-car-accidents-and-whos-at-fault) [Bart Durham Injury Law](https://news.bartdurham.com/blog/author/bart-durham-injury-law) 12/08/2023 [Driver Negligence](https://news.bartdurham.com/blog/tag/driver-negligence), [Fatal Accidents](https://news.bartdurham.com/blog/tag/fatal-accidents), [Kentucky](https://news.bartdurham.com/blog/tag/kentucky), [Tennessee](https://news.bartdurham.com/blog/tag/tennessee), [Big Truck Accidents](https://news.bartdurham.com/blog/tag/big-truck-accidents), [New Car](https://news.bartdurham.com/blog/tag/new-car), [Distracted Driving](https://news.bartdurham.com/blog/tag/distracted-driving), [Personal Injury Lawyer](https://news.bartdurham.com/blog/tag/personal-injury-lawyer), [Commercial Vehicle Accidents](https://news.bartdurham.com/blog/tag/commercial-vehicle-accidents) [Wrecks with Delivery Drivers Require Personal Injury Professionals](https://news.bartdurham.com/blog/wrecks-with-delivery-drivers-require-personal-injury-professionals) --- ![Bart Durham Injury Law](https://news.bartdurham.com/hs-fs/hubfs/raw_assets/public/Bart_Durham_December2023/images/footer-logo.png?width=2680&name=footer-logo.png "Bart Durham Injury Law") Bart Durham Injury Law 406 11th Avenue North, Suite 200 Nashville, TN 37203 - [Toll Free: 800-844-1712](tel:800-844-1712) - [Phone: 615-242-9000](tel:615-242-9000) - Fax: ‍615-254-6562 - [Nashville Law Office Map](https://maps.app.goo.gl/TNSQJU4WHTovJQdN7) - [Kentucky Law Office Map](https://maps.app.goo.gl/feadMtHztUmSUpXm6) - [Toll Free: 800-844-1712](tel:800-844-1712) - [Phone: 615-242-9000](tel:615-242-9000) - Fax: ‍615-254-6562 - [Nashville Law Office Map](https://maps.app.goo.gl/TNSQJU4WHTovJQdN7) - [Kentucky Law Office Map](https://maps.app.goo.gl/feadMtHztUmSUpXm6) [Write a Review](https://www.locationrater.com/tp/5xloZz/) Tell us how we are doing. We are interested in your feedback. © 2023 by Bart Durham Injury Law. All rights reserved. [Disclaimer](https://bartdurham.com/disclaimer/) | [Kentucky Disclaimer](https://bartdurham.com/disclaimer-ky/) | [Site Map](https://bartdurham.com/sitemap) | [Privacy Policy](https://bartdurham.com/privacy-policy/) Some services may be performed by others. Horton - [Nashville Web Design](https://www.hortongroup.com/web-design) & [SEO Services](https://www.hortongroup.com/nashville-seo) [![Lawyers Of Distinction 2023](https://news.bartdurham.com/hubfs/raw_assets/public/Bart_Durham_December2023/images/BD-FOOTER-LOGO-1.png)](https://www.thelawyersofdistinction.com/profile/blair-durham/) [![Military Business](https://news.bartdurham.com/hubfs/raw_assets/public/Bart_Durham_December2023/images/BD-FOOTER-LOGO-2.png)](https://business.mybaseguide.com/business/bartdurhaminjurylaw_5655ed245c37) [![The National Trial Lawyers](https://news.bartdurham.com/hubfs/raw_assets/public/Bart_Durham_December2023/images/BD-FOOTER-LOGO-3.png)](http://thenationaltriallawyers.org/) [![Best Car Accident Lawyers in Nashville](https://news.bartdurham.com/hubfs/raw_assets/public/Bart_Durham_December2023/images/BD-FOOTER-LOGO-4.png)](https://www.forbes.com/advisor/legal/personal-injury/best-personal-injury-lawyers-nashville-tn/?award=best-personal-injury-lawyers-nashville-tn-award-2024-blair-p-durham) ```json { "@context" : "https://schema.org", "@type" : "BlogPosting", "author" : { "@type" : "Person", "name" : "Bart Durham Injury Law", "url" : "https://news.bartdurham.com/blog/author/bart-durham-injury-law" }, "dateModified" : "2018-12-20T19:28:12.425Z", "datePublished" : "2018-09-24T16:01:30.000Z", "headline" : "Proton Pump Inhibitors: How Long Term Use is Linked to Deadly Side Effects", "image" : [ "https://news.bartdurham.com/hubfs/photos/Pills-Drugs-1.png" ], "mainEntityOfPage" : { "@id" : "https://news.bartdurham.com/blog/2018/09/proton-pump-inhibitors-how-long-term-use-is-linked-to-deadly-side-effects", "@type" : "WebPage" }, "publisher" : { "@type" : "Organization", "logo" : { "@type" : "ImageObject", "url" : "https://news.bartdurham.com/hubfs/BD-VECTOR_MAIN-NAV-LOGO-WHITE.png" }, "name" : "Bart Durham Injury Law" } } ```